|
KMID : 0359319940340020375
|
|
Korean Journal of Veterinary Research
1994 Volume.34 No. 2 p.375 ~ p.379
|
|
|
Studies on the teratogenicity of folpet in the developing chick embryo
|
|
|
|
|
Abstract
|
|
|
A teratogenicity test of ´folpet was carried out in the developing chick embryos to investigate and validate the safety of rural environmental hazardous materials. Folpet was administered to chick embryos´ yolk sac at a rate of 0.l㎎ and 0.0l㎎ per SPF eggs at 96 hours of incubation. The morphological changes were examined.
Fertility ratio of SPF eggs used was 94.9%. Hatching rate of untreated control group was 74.4% and the group dosed with 100u1 of corn oil into the yolk sac was 70.0%. The LD_(50) of folpet was 0.663㎎/100ul/egg. After hatching, mean body weight, body length, claw length and beak length of high and low dose administered groups were not significantly different from untreated and vehicle control group. There was no abnormal appearence in all the groups. Therefore it seems that, within the doses applied, folpet dose not induce potential teratogenicity in the developing chick embryos.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|